EVIDENCE SUPPORTING A NEW PARADIGM FOR PREVENTION AND IMPROVED HEALTH OUTCOMES

The unique proposition of the Documenting Hope Project is that it truly represents the future of medicine with an approach that is personalized, integrative, and inclusive of a variety of therapeutics that are properly sequenced and implemented in a way that is both reflexive and responsive. This approach relies on assessments that are comprehensive and bioindividual and take into account individual nutritional, metabolic, gastrointestinal, genomic, environmental, developmental, energetic and other variables.

Lambert B, Kobliner V. A compromised generation : the epidemic of chronic illness in America’s children [Internet]. 1st Sentient Publications. Boulder, CO: Sentient Publications; 2010. xiv, 358 p.

McCloud E, Papoutsakis C. A medical nutrition therapy primer for childhood asthma: current and emerging perspectives. J Am Diet Assoc. 2011 Jul;111(7):1052–64.

 

BIOINDIVIDUALITY AND PERSONALIZED MEDICINE

The unique proposition of the Documenting Hope Project is that it truly represents the future of medicine with an approach that is personalized, integrative, and inclusive of a variety of therapeutics that are properly sequenced and implemented in a way that is both reflexive and responsive. This approach relies on assessments that are comprehensive and bioindividual and take into account individual nutritional, metabolic, gastrointestinal, genomic, environmental, developmental, energetic and other variables.

Brookes KJ, Hawi Z, Park J, Scott S, Gill M, Kent L. Polymorphisms of the steroid sulfatase (STS) gene are associated with attention deficit hyperactivity disorder and influence brain tissue mRNA expression. Am J Med Genet B Neuropsychiatr Genet. 2010;153B(8):1417-24.

D’Auria E, Miraglia Del Giudice M, Barberi S, Mandelli M, Verduci E, Leonardi S, et al. Omega-3 fatty acids and asthma in children. Allergy Asthma Proc. 2014;35(3):233-40.

Ergul E, Sazci A, Kara I. Methylenetetrahydrofolate reductase gene polymorphisms in Turkish children with attention-deficit/hyperactivity disorder. Genet Test Mol Biomarkers. 2012;16(1):67-9.

Gadow KD, Roohi J, DeVincent CJ, Kirsch S, Hatchwell E. Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder. J Autism Dev Disord. 2009;39(11):1542-51.

Gebril OH, Meguid NA. HFE gene polymorphisms and the risk for autism in Egyptian children and impact on the effect of oxidative stress. Dis Markers. 2011;31(5):289-94.

Gordon E, Koslow SH. Integrative neuroscience and personalized medicine. New York: Oxford University Press; 2011. xxi, 323 p. p.

Hammons AL, Summers CM, Woodside JV, McNulty H, Strain JJ, Young IS, et al. Folate/homocysteine phenotypes and MTHFR 677C>T genotypes are associated with serum levels of monocyte chemoattractant protein-1. Clin Immunol. 2009;133(1):132-7.

Kalkan G, Yigit S, Karakus N, Ates O, Bozkurt N, Ozdemir A, et al. Methylenetetrahydrofolate reductase C677T mutation in patients with alopecia areata in Turkish population. Gene. 2013;530(1):109-12.

Kapka-Skrzypczak L, Niedzwiecka J, Cyranka M, Kruszewski MK, Skrzypczak M, Wojtyla A. [Nutrigenomics – perspectives of personalized nutrition]. Pediatr Endocrinol Diabetes Metab. 2011;17(4):222-6.

Lattka E, Klopp N, Demmelmair H, Klingler M, Heinrich J, Koletzko B. Genetic variations in polyunsaturated fatty acid metabolism–implications for child health? Ann Nutr Metab. 2012;60 Suppl 3:8-17.

Nicholson JK, Holmes E, Wilson ID. Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol. 2005;3(5):431-8.

Patel CJ, Sivadas A, Tabassum R, Preeprem T, Zhao J, Arafat D, et al. Whole genome sequencing in support of wellness and health maintenance. Genome Med. 2013;5(6):58.

Rosa JS, Oliver SR, Flores RL, Ngo J, Milne GL, Zaldivar FP, et al. Altered inflammatory, oxidative, and metabolic responses to exercise in pediatric obesity and type 1 diabetes. Pediatr Diabetes. 2011 Aug;12(5):464–72.

Simopoulos AP. Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk. Exp Biol Med (Maywood). 2010;235(7):785-95.

 

REMISSION/RECOVERY/NEUROPLASTICITY

Much of the evidence for remission or full recovery of chronic illnesses lies in the category of anecdote. One of the central objectives of the Documenting Hope Project is to record (scientifically and on film) healing as it happens. Anecdotal healing or remission from disease is a phenomenon that has been reported for centuries, but few attempts have been made to document a reversal of symptoms in a rigorously scientific study.

The Documenting Hope Project builds on a body of medical literature demonstrating that the human body has an inherent capacity to heal. A goal of the Project is to gain new insight into neuroplasticity, regenerative medicine and other emerging fields of inquiry.

Following is cataloguing of some of the medical literature and the documentation of anecdotal successes in recovering children.

Adams C. A real boy: a true story of autism, early intervention, and recovery. Berkeley Trade pbk. ed. New York: Berkley Books; 2005. xiv, 318 p. p.

Bickle Graz M, Monnier M, von Laer Tschudin L, Truttmann AC. Normal neurodevelopmental outcome despite severe and early extensive encephalomalacia: plasticity, repair or magic? Dev Med Child Neurol. 2013;55(9):868-9.

Bilbo SD, Wray GA, Perkins SE, Parker W. Reconstitution of the human biome as the most reasonable solution for epidemics of allergic and autoimmune diseases. Med Hypotheses. 2011;77(4):494-504.

Blomberg H, Dempsey M, Phua SS. Movements that heal: rhythmic movement training and primitive reflex integration. 1st. ed. East Melbourne, Vic.: Beyond the Sea Squirt; 2008. xii, 244 pages p.

Blum SS, Bender M. The immune system recovery plan: a doctor’s 4-step program to treat autoimmune disease. First Scribner hardcover edition. ed. New York: Scribner; 2013. Xii, 370 pages p.

Brockley A, Urdiales K. Autoimmune: the cause and the cure. Spearfish, SD: Nature Had It First; 2011. 175 p. p.

Buckley JA. Healing our autistic children : a medical plan for restoring your child’s health. 1st ed. New York: Palgrave Macmillan; 2010. xiv, 238 p. P.

Dickens TG. Accept no autism!: our family’s story of recovery. Snellville, GA: Jebaire Pub., LLC; 2010.

Doman GJ. What to do about your brain-injured child, or your brain-damaged, mentally retarded, mentally deficient, cerebral-palsied, emotionally disturbed, spastic, flaccid, rigid, epileptic, autistic, athetoid, hyperactive child. 1st ed. Garden City, N.Y.,: Doubleday; 1974. xv, 291 p. p.

Doidge, N. The Brain that Changes Itself: Stories of personal triumph from the frontiers of brain science. New York, NY: Viking; 2007.

Doidge, N. The Brain’s Way of Healing. New York, NY: Viking; 2016.

Gilbere G. I was poisoned by my body–I have a gut feeling you could be, too! : the odyssey of a doctor who reversed fibromyalgia, leaky gut syndrome, multiple allergic responses, naturally– and her life 10 years after recovery. 2nd ed. Lancaster, OH: Lucky Press; 2007. 303 p. P.

Giustra-Kozek J. Healing without hurting: treating ADHD, apraxia, and autism spectrum disorders naturally and effectively without harmful medication. Howard Beach, NY: Changing Lives Press; 2014. xiii, 370 p. p.

Gozzi TG, Simm PJ, Cameron FJ. Spontaneous recovery of steroid-induced osteopenia. J Paediatr Child Health. 2006;42(1-2):68-9.

Guyol G. Who’s crazy here?: Steps to recovery without drugs for: ADD/ADHD, addiction & eating disorders, anxiety & PTSD, depression, bipolar disorder, schizophrenia, autism. 1st U.S. ed. Stonington, CT: Ajoite Pub.; 2010. 123 p. P.

Hochberg Z, Feil R, Constancia M, Fraga M, Junien C, Carel JC, et al. Child health, developmental plasticity, and epigenetic programming. Endocr Rev. 2011;32(2):159-224.

Hyman M. The UltraMind solution: fix your broken brain by healing your body first : the simple way to defeat depression, overcome anxiety and sharpen your mind. 1st Scribner hardcover ed. New York: Scribner; 2008. xiv, 447 p. p.

Kaufman RK. Autism breakthrough: the groundbreaking method that has helped families all over the world. First edition. ed. New York: St. Martin’s Press; 2014. x, 353 pages p.

McCarthy J, Kartzinel J. Healing and preventing autism: a complete guide. New York: Dutton; 2009. 400 p. p.

Lambert B, Kobliner V. A compromised generation : the epidemic of chronic illness in America’s children. 1st Sentient Publications ed. Boulder, CO: Sentient Publications; 2010. xiv, 358 p. p.

O’Hara NH, Szakacs GM. The recovery of a child with autism spectrum disorder through biomedical interventions. Altern Ther Health Med. 2008;14(6):42-4.

Pilecki W, Masgutova S, Kowalewska J, Masgutov D, Akhmatova N, Poreba M, et al. The impact of rehabilitation carried out using the Masgutova Neurosensorimotor Reflex Integration method in children with cerebral palsy on the results of brain stem auditory potential examinations. Adv Clin Exp Med. 2012;21(3):363-71.

Romaniec M. Victory over autism: lessons on raising an autism-free child. New York, NY: Skyhorse Publishing; 2015. pages cm p.

Sears RW. The autism book: what every parent needs to know about early detection, treatment, recovery, and prevention. 1st ed. New York, NY: Little, Brown; 2010. xv, 398 p.p.

Seroussi K. Unraveling the mystery of autism and pervasive developmental disorder : a mother’s story of research and recovery. New York: Simon & Schuster; 2000. 288 p. p.

Tracy J, Hampstead B, Sathian K. Cognitive plasticity in neurologic disorders. Oxford: Oxford University Press; 2015. xiii, 406 pages p.

Wahls TL, Adamson E. The Wahls protocol: how I beat progressive MS using Paleo principles and functional medicine. New York: Avery, a member of Penguin Group (USA); 2014. viii, 421 pages p.

Waterland RA, Jirtle RL. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition. 2004;20(1):63-8.

Whittaker F. Rheumatoid remedies: a collection of more than 70 pages of nutritional and drug-free options to promote recovery from rheumatoid arthritis and associated inflammatory diseases. 1st ed. Kaitaia, N.Z.: Dancing Lion Press; 2009. 84 p. P.

 

RECOVERY STORIES

Cimador, Cimador & Cimador, Christopher. The Race to Recovery. Colleen McNamara Cimador. 2014.

Doidge, N. The Brain that Changes Itself: Stories of personal triumph from the frontiers of brain science. New York, NY: Viking; 2007.

Dickens TG. Accept no autism!: our family’s story of recovery. Snellville, GA: Jebaire Pub., LLC; 2010.

Guistra-Kozek, Jennifer. Healing Without Hurting. Changing Lives Press. 2014.

Hinds, Marcia. I know You’re In There. Hindsight Press. Los Angeles, CA. 2014. Kindle Edition.